I think it actually helps reduce eyes strain. I have it setup in a standing desk like setup so it's ~15" in front of me, so distance is just few inches apart than a standard distance to a laptop screen. My eyes don't get tired at all, where as looking at my laptop screen does, but that's probably due to the pixel density in addition to the reflectiveness.
I've found it to be rather intrusive and annoying, especially compared to the ZR2440w's coating.